halazepam

Halazepam is a benzodiazepine derivative that was used primarily as an anxiolytic to relieve anxiety, nervousness, and tension associated with anxiety disorders. It exerts its effects by acting as a positive allosteric modulator of the GABA(A) receptor complex in the central nervous system, enhancing the inhibitory effect of gamma-aminobutyric acid (GABA). Halazepam also has anticonvulsant, sedative, and muscle relaxant properties. It was considered less toxic than chlordiazepoxide or diazepam. The drug was invented by Schlesinger Walter in the United States and marketed from 1981 under various brand names including Paxipam (US), Alapryl (Spain), and Pacinone (Portugal). However, it is no longer commercially available in the United States after being withdrawn for poor sales by its manufacturer Schering in 2009[2][4][7].

Brand names

PaxipamAlaprylPacinone

Other names

halazepam