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Drug intelligence / Profile preview
Halobetasol propionate 0.05% lotion
- Development stage
- Phase 4
- Lead developer
- Sun Pharma
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Halobetasol propionate 0.05% lotion (code name 000-0551) is a super-high potency topical corticosteroid developed by Therapeutics, Inc. and marketed as Ultravate Lotion. It is indicated for the topical treatment of plaque psoriasis and other corticosteroid-responsive dermatoses in patients 12 years of age and older. The drug functions as a glucocorticoid receptor agonist, exerting anti-inflammatory, antipruritic, and vasoconstrictive effects by inhibiting the release of inflammatory mediators and suppressing the immune response in the skin. Unlike the 0.01% formulation (Bryhali), which is applied once daily, the 0.05% lotion is typically applied twice daily for a maximum duration of two weeks.
- Brand names
- Ultravate
- Other names
- Halobetasol propionate lotionHalobetasol propionate 0.05% lotion
02
Targets
GR (Glucocorticoid receptor)
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