haloperidol

Haloperidol is a first-generation (typical) antipsychotic of the butyrophenone class, primarily used to treat schizophrenia, acute psychosis, and tics associated with Tourette's syndrome. It is also indicated for severe behavioral problems in children and for managing agitation, delirium, and mania. Haloperidol acts mainly as a potent antagonist of dopamine D2 receptors in the brain, reducing abnormal excitement and psychotic symptoms. It can be administered orally or by intramuscular/intravenous injection; long-lasting decanoate formulations are available for monthly administration. The drug was developed by Paul Janssen's team in Belgium in 1958 and remains on the WHO Model List of Essential Medicines[1][6][7].

Brand names

HaldolSerenaceAloperidinDozicPernox

Other names

氟哌啶醇 (Chinese)Haloperidolumγ-(4-(p-chlorophenyl)-4-hydroxypiperidino)-p-fluorbutyrophenone1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine