Drug intelligence / Profile preview

haloxon

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Haloxon is an organophosphorus anthelmintic agent used in veterinary medicine, primarily for the treatment and control of gastrointestinal roundworm infections in cattle and other ruminants. It is effective against nematodes such as Haemonchus, Ostertagia, Trichostrongylus, Cooperia, Strongyloides papillosus, Bunostomum trigonocephalum, and Oesophagostomum venulosum. Haloxon's mechanism of action involves antagonism of cholinesterase enzymes (cholinesterase inhibitor), leading to paralysis and death of susceptible parasites. The drug is more active against adult worms than larval stages for some species. It should not be used concurrently with other cholinesterase-inhibiting agents due to risk of toxicity[1][4][5][7].

Brand names
Halox
Other names
haloxonahaloxonehaloxonum
02

Targets

ButyrylcholinesteraseAcetylcholinesterase

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