Drug intelligence / Profile preview

hamamelis virginiana distillate

Development stage
Phase 4
Lead developer
Schwabe
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Hametum Wund- und Heilsalbe is a topical herbal medicinal ointment containing Hamamelis virginiana distillate as its active ingredient. Developed by Dr. Willmar Schwabe GmbH & Co. KG, it is primarily used for the treatment of minor skin injuries, abrasions, and localized inflammations of the skin and mucous membranes. The therapeutic effect is attributed to tannins within the distillate, which form a protective protein layer on the skin, providing anti-inflammatory, anti-pruritic (itch-reducing), and mild hemostatic (bleeding-stopping) properties. It has also been evaluated in Phase IV clinical trials for managing drug-induced skin disorders, such as dryness and fissures caused by systemic medications.

Brand names
Hametum Wund- und HeilsalbeHametum
Other names
Hamamelis virginiana L. distillateHamamelis distillatewitch hazel distillate

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