hangeshashinto

TJ-14, also known as Hangeshashinto or Ban Xia Xie Xin Tang, is a traditional Kampo (Japanese herbal) medicine composed of seven crude drugs: Pinellia Tuber, Scutellaria Root, Coptis Rhizome, Processed Ginger, Ginseng, Jujube, and Glycyrrhiza. It is primarily used in Japan for the treatment of gastrointestinal disorders, including chemotherapy-induced oral mucositis and radiation-induced enteritis. The therapeutic effects of TJ-14 are attributed to its multi-component nature, which exerts anti-inflammatory and cytoprotective actions. Specifically, it has been shown to inhibit the production of prostaglandin E2 (PGE2) by suppressing cyclooxygenase-2 (COX-2) expression and to reduce oxidative stress. In clinical trials, it is often compared to standard treatments like loperamide for managing diarrhea and mucosal damage associated with cancer therapies.

Brand names

Tsumura Hangeshashinto

Other names

Ban Xia Xie Xin TangHangeshashinto