Drug intelligence / Profile preview

Harpagyl

Development stage
Unknown
Lead developer
Laboratoires Audevard
Modality
Small Molecules
Administration
Oral
01

Overview

Harpagyl is a veterinary nutraceutical supplement developed by Laboratoires Audevard specifically for equine joint support. It is formulated to provide nutritional support for the increased musculoskeletal needs of active and older horses, particularly those experiencing joint pain, stiffness, or locomotor discomfort associated with conditions like osteoarthritis. The primary active ingredient is *Harpagophytum procumbens* (Devil's Claw), which is standardized for its content of harpagosides. Harpagosides are bioactive compounds known for their natural anti-inflammatory and analgesic properties, primarily acting through the inhibition of inflammatory pathways. The product is also enriched with plant-based omega-3 fatty acids derived from linseed and linseed oil to further support joint health. Due to the presence of harpagosides, Harpagyl is subject to anti-doping regulations in competitive equestrian sports and must be withdrawn at least 48 hours prior to competition.

Brand names
Harpagyl
Other names
Harpagyl-Laboratoires Audevard-Equine joint support for horses
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX5 (Arachidonate 5-lipoxygenase)

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