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HAuNS@PEG-bio
- Development stage
- Preclinical
- Modality
- Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
HAuNS@PEG-bio is an experimental **biotin-decorated hollow gold nanoshell nanoparticle** developed as a theranostic agent for breast cancer. It is produced by generating hollow gold nanoshells and further surface-functionalizing them with biotin-PEG-SH to improve tumor-cell targeting. In the cited preclinical work, the construct is intended to support **NIR-II photothermal therapy**, **CT and infrared thermal imaging guidance**, and **radiosensitization**; its therapeutic concept relies on strong X-ray absorption by gold and photothermal heating that can improve tumor oxygenation, thereby enhancing radiotherapy and promoting immunogenic cell death in tumors. The available evidence appears to be preclinical and publication-based rather than from a named commercial development program.
- Other names
- biotin-decorated hollow gold nanoshellbiotin-PEG-SH modified hollow gold nanoshell
02
Targets
DNA
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