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hawthorn

Development stage: Preclinical
Administration: Oral

Overview

Hawthorn refers to the leaves, berries, flowers, and roots of plants in the Crataegus genus (including C. monogyna, C. oxyacantha, C. laevigata, C. pinnatifida, and C. mexicana) that are used medicinally. It contains flavonoids with antioxidant properties that appear to improve blood circulation and affect blood flow from the heart. Hawthorn has positive inotropic effects, causes peripheral vasodilation, increases myocardial perfusion, and may have antiarrhythmic activity by increasing the refractory period.

Brand names: CardiplantCrataegisanCrataeguttFarosKorodinLI 132LI132LI-132WS 1442WS1442WS-1442
Other names: English hawthornHawHawthornMaybushWhitethornAubepineChinese hawthornHagthornHedgethornLadies' meatMayMayblossomMayflowerMaythornOneseed hawthornShanzhaTejocoteRaiz de tejocote

Targets

EPAC2 (Rap guanine nucleotide exchange factor 4)ACE (Angiotensin Converting Enzyme)PKG (cGMP-dependent protein kinase I alpha)PDE (Phosphodiesterase family)

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