Drug intelligence / Profile preview

HBO-001

Development stage
Preclinical
Lead developer
HysensBio
Modality
Peptides
Administration
Topical
01

Overview

HBO-001 is a therapeutic candidate being developed by HysensBio for the treatment of amelogenesis imperfecta, a rare genetic disorder characterized by defective tooth enamel formation. The drug is part of HysensBio's dental regeneration pipeline and utilizes a proprietary peptide technology derived from Copine-7 (CPNE7). CPNE7 is a signaling protein that plays a critical role in odontoblast differentiation and the mineralization of dental tissues. By mimicking the activity of CPNE7, HBO-001 is designed to stimulate the natural regeneration of enamel and dentin, potentially restoring the structural integrity of teeth in patients with hereditary enamel defects and reducing the need for invasive restorative dental procedures.

02

Targets

NCL (Nucleolin)

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