Drug intelligence / Profile preview

HCP1007

Development stage
Phase 1
Lead developer
Hanmi Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

HCP1007 is a fixed-dose combination (FDC) drug candidate developed by Hanmi Pharmaceutical for the treatment of dyslipidemia, specifically targeting patients with hypercholesterolemia and hypertriglyceridemia. It combines rosuvastatin, a potent HMG-CoA reductase inhibitor (statin), with omega-3 fatty acids (typically eicosapentaenoic acid and docosahexaenoic acid). Rosuvastatin lowers LDL cholesterol by inhibiting the rate-limiting enzyme in cholesterol biosynthesis, while omega-3 fatty acids reduce serum triglyceride levels by inhibiting hepatic lipogenesis and increasing fatty acid oxidation. This combination therapy is designed to provide a comprehensive lipid-lowering effect and improve patient compliance by reducing the pill burden associated with managing mixed dyslipidemia.

Other names
rosuvastatin + omega-3 fatty acids
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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