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Drug intelligence / Profile preview
HD-MAP seasonal influenza vaccine
- Development stage
- Unknown
- Lead developer
- Vaxxas
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Transdermal
01
Overview
The HD-MAP seasonal influenza vaccine is a needle-free, quadrivalent inactivated influenza vaccine (IIV4) delivered via Vaxxas' proprietary High-Density Microarray Patch (HD-MAP) technology. The patch consists of an ultra-high-density array of micro-projections that deliver split inactivated influenza virus antigens directly to the immune-cell-rich layers of the skin. This delivery method is designed to enhance immunogenicity compared to traditional intramuscular injection while offering advantages such as thermostability (stable at 40°C for 12 months) and the potential for self-administration. The vaccine targets four strains of influenza (two A and two B) and is currently in Phase I clinical development for the prevention of seasonal influenza in healthy adults.
- Other names
- Vaxxas HD-MAP influenza vaccineHigh-Density Microarray Patch seasonal influenza vaccine
02
Targets
HA (Hemagglutinin)
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