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HDV-Insulin Lispro
- Development stage
- Phase 2
- Lead developer
- Diasome Pharmaceuticals
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Subcutaneous
01
Overview
HDV-Insulin Lispro is a novel formulation that combines insulin lispro with Hepatocyte-Directed Vesicles (HDV) technology. This formulation is designed to target insulin delivery specifically to the liver, reestablishing the liver as a major metabolic modulator of glucose metabolism. The technology appears to enhance the antihyperglycemic effect of insulin by stimulating hepatic glucose uptake and/or glycogen storage in insulin-deficient patients. HDV-Insulin Lispro works by delivering insulin more directly to hepatocytes, potentially allowing for improved glycemic control with reduced risk of hypoglycemia compared to standard insulin lispro.
- Other names
- Hepatocyte-Directed Vesicles-insulin lispro
02
Targets
INSR (Insulin receptor)IGF-1R (Insulin-like growth factor 1 receptor)
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