Drug intelligence / Profile preview

Hecolin + hepatitis B vaccine

Development stage
Unknown
Lead developer
Xiamen Innovax Biotech
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Hecolin + hepatitis B vaccine is a co-administered vaccine regimen developed by Xiamen Innovax Biotech for the simultaneous prevention of hepatitis E and hepatitis B infections. Hecolin (HEV 239) is a recombinant virus-like particle (VLP) vaccine expressed in *Escherichia coli*, representing the structural protein of the hepatitis E virus (genotype 1). The hepatitis B component is a recombinant vaccine containing the hepatitis B surface antigen (HBsAg). This combination is primarily evaluated for safety and immunogenicity in healthy adults to simplify immunization schedules in endemic regions where both viruses are prevalent.

Brand names
Hecolin
Other names
Recombinant Hepatitis E Vaccine (Escherichia Coli)Recombinant Hepatitis B Vaccinehepatitis B vaccine-Xiamen Innovax Biotech Co., Ltd-hepatitis E
02

Targets

HBsAg (Hepatitis B surface antigen)HEV ORF2 (Hepatitis E virus capsid protein)

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