hedera helix leaf

Hedera helix leaf extract, derived from the common ivy plant, is a herbal medicinal product widely utilized as an expectorant and mucolytic agent for respiratory conditions. Its therapeutic efficacy is primarily attributed to triterpene saponins, most notably alpha-hederin. Alpha-hederin exerts its effect by inhibiting the internalization of beta-2 adrenergic receptors (ADRB2) in bronchial smooth muscle and alveolar cells. By maintaining a higher density of these receptors on the cell surface, the extract enhances the responsiveness to endogenous adrenaline, resulting in bronchodilation, increased surfactant production, and reduced mucus viscosity. Zhejiang Conba Pharmaceutical Co., Ltd. is a significant developer and manufacturer of this extract, particularly in the form of oral solutions indicated for the treatment of acute tracheobronchitis and chronic inflammatory bronchial diseases.

Brand names

ProspanHedelixAbrilarHelical

Other names

Ivy leaf extractCommon ivy leafHederae helicis folium