Drug intelligence / Profile preview

helianthus annuus pollen

Development stage
Unknown
Modality
Recombinant Proteins and Enzymes
Administration
Percutaneous, Intradermal
01

Overview

Helianthus annuus pollen, derived from the common sunflower, is utilized in clinical allergology primarily as an allergen extract for the diagnosis and treatment of sunflower-related hypersensitivity. The pollen contains several allergenic proteins, most notably profilins (such as Hel a 2), which are responsible for cross-reactivity with other plant pollens and foods. In diagnostic applications, the extract is used in skin prick testing to identify individuals sensitized to sunflower pollen, which is a significant cause of occupational allergic rhinitis, conjunctivitis, and asthma among workers in sunflower processing industries. Therapeutically, it may be employed in allergen-specific immunotherapy (AIT) to induce immunological tolerance by modulating T-cell and B-cell responses to the pollen's constituent allergens.

Other names
sunflower pollensunflower pollen extract
02

Targets

IgE (Immunoglobulin E)

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