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helleborus niger

Development stage: Preclinical
Lead developer: Geriatrische Rehabilitationsklinik Alexander von Humboldt
Administration: Subcutaneous

Overview

Helleborus niger is a botanical extract derived from the Christmas rose plant, primarily used as an anthroposophic or homeopathic preparation. It has been studied as a subcutaneous injection (specifically in a 12x homeopathic potency) at the Geriatrische Rehabilitationsklinik Alexander von Humboldt as an adjunctive treatment for elderly patients with unspecified dementia. The extract contains bioactive constituents such as ecdysteroids and bufadienolides, which are associated with immunomodulatory, anti-inflammatory, and antioxidant activities. In the context of dementia, it is intended to complement conventional pharmaceutical treatments by providing neuroprotective and analgesic support.

Other names: hellebore nigerChristmas roseHelleborus niger L.

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