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HEM1036 is an orally administered live biotherapeutic product (LBP) containing a specific strain of the bacterium *Limosilactobacillus fermentum*. Developed by the South Korean biotechnology company HEM Pharma, it is specifically designed to treat Low Anterior Resection Syndrome (LARS), a condition characterized by bowel dysfunction (including fecal urgency, frequency, and incontinence) that often follows sphincter-preserving surgery for rectal cancer. HEM1036 aims to restore the balance of the gut microbiome, which is typically disrupted post-surgery, to improve intestinal homeostasis and alleviate clinical symptoms. The candidate is currently being evaluated in Phase 2 clinical trials.
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