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**Hemay028** is a small-molecule **phosphodiesterase 4 (PDE4) inhibitor** developed by **Tianjin Hemay Pharmaceutical** (also referred to as Tianjin Hemay Oncology Pharmaceutical Co., Ltd. or Tianjin Hemei Biological Technology Co., Ltd.) for dermatological indications. It is formulated as **Hemay808**, a topical ointment, and has been investigated in Phase I and Phase II clinical trials for **atopic dermatitis**, with the Phase II trial (NCT04352595) evaluating efficacy and safety in patients.[1][9][11][14][15]
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