Drug intelligence / Profile preview

heme iron polypeptide

Development stage
Phase 4
Lead developer
Colorado Biolabs
Modality
Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Heme iron polypeptide is an oral iron supplement derived from hemoglobin. It is used to treat or prevent low levels of iron in the blood, particularly in cases of anemia due to chronic disease, pregnancy, kidney failure, or when patients cannot tolerate traditional non-heme (ferrous) oral irons. Heme iron is absorbed via a different pathway than non-heme irons and may be better tolerated with fewer gastrointestinal side effects. It is not FDA-approved as a pharmaceutical drug but is widely available as a dietary supplement and sometimes included in combination products for anemia management[1][2][3]. Its primary mechanism involves providing bioavailable elemental iron for incorporation into hemoglobin and other essential proteins involved in oxygen transport[2][5].

Brand names
Proferrin ClearProferrin-ES
Other names
iron heme polypeptideheme iron polypepHIP
02

Targets

SLC46A1 (Proton-coupled folate transporter)

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