Drug intelligence / Profile preview

Hemospray

Development stage
Phase 4
Lead developer
Cook Medical
Administration
Endoscopic
01

Overview

Hemospray (TC-325) is a proprietary, inorganic, mineral-based hemostatic powder developed by Cook Medical for the treatment of non-variceal gastrointestinal bleeding. Delivered endoscopically via a pressurized CO2 delivery system, the powder is non-contact and non-thermal, allowing for the treatment of large-surface-area bleeding where traditional mechanical or thermal therapies may be difficult to apply. Upon contact with blood or moisture at the bleeding site, the powder absorbs water to form a cohesive and adhesive gel-like matrix. This physical barrier mechanically seals the bleeding vessel while simultaneously concentrating clotting factors and platelets to accelerate the natural coagulation cascade. It is primarily indicated for upper and lower gastrointestinal bleeding, including peptic ulcers, post-polypectomy bleeding, and malignancy-related hemorrhage.

Brand names
Hemospray
Other names
hemostatic powderTC-325TC325TC 325

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