Drug intelligence / Profile preview

Henan Normal Univ. ERK1 compound 21y

Development stage
Preclinical
Lead developer
Henan Normal University
01

Overview

Henan Normal Univ. ERK1 compound 21y: sourced facts only. name: "Furthermore, label-free drug affinity responsive target stability (DARTS) and LC-MS/MS proteomics techniques revealed that 21y directly targets ERK1/2." [PMID:39950600]; target: "Furthermore, label-free drug affinity responsive target stability (DARTS) and LC-MS/MS proteomics techniques revealed that 21y directly targets ERK1/2." [PMID:39950600]; developer: "State Key Laboratory of Antiviral Drugs, Pingyuan Laboratory, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China." [PMID:39950600]; stage: "In vivo studies confirmed that 21y strongly inhibited tumor growth and lung metastasis in breast cancer." [PMID:39950600]

02

Targets

MAPK3 (Mitogen-activated protein kinase 1)

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