Drug intelligence / Profile preview

Henan Normal Univ. STING compound 3S-12

Development stage
Preclinical
Lead developer
Henan Normal University
01

Overview

Henan Normal Univ. STING compound 3S-12: sourced facts only. name: "The representative compound 3S-12 exhibited potent STING inhibitory activity with IC50 of 0.124 μM for m-STING and 0.533 μM for h-STING." [PMID:41066957]; target: "The representative compound 3S-12 exhibited potent STING inhibitory activity with IC50 of 0.124 μM for m-STING and 0.533 μM for h-STING." [PMID:41066957]; developer: "Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, PR China." [PMID:41066957]; stage: "In the cisplatin-induced acute kidney injury model, 3S-12 significantly alleviated tissue injury and inflammation." [PMID:41066957]

02

Targets

STING (Stimulator of interferon genes protein)

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