Henan Univ. of Chinese Medicine LSD1 compound S3

Henan Univ. of Chinese Medicine LSD1 compound S3: sourced facts only. name: "After rational modification, compound S3 was obtained with significantly improved LSD1 inhibition (IC₅₀ = 2.30 μM), approximately 7-fold more potent than the silybin." [PMID:42612268]; target: "After rational modification, compound S3 was obtained with significantly improved LSD1 inhibition (IC₅₀ = 2.30 μM), approximately 7-fold more potent than the silybin." [PMID:42612268]; developer: "Academy of Chinese Medical Sciences; Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao; Henan University of Chinese Medicine, Zhengzhou 450046, China." [PMID:42612268]; stage: "In APP/PS1 mice, S3 upregulated hippocampal H3K9me2, suppressed neuroinflammation and Aβ deposition, and improved cognitive function." [PMID:42612268]