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Hengyan Kuntai Capsules
- Development stage
- Phase 4
- Lead developer
- Xintian Pharmaceutical
- Administration
- Oral
01
Overview
Hengyan Kuntai Capsules is a Traditional Chinese Medicine (TCM) formulation primarily used in China for the treatment of menopausal syndrome and diminished ovarian reserve (DOR). The capsule is composed of six traditional herbal ingredients: *Rehmannia glutinosa*, *Coptis chinensis*, *Paeonia lactiflora*, *Scutellaria baicalensis*, *Poria cocos*, and *Asini Corii Colla*. Mechanistically, the formulation is believed to regulate the hypothalamic-pituitary-ovarian (HPO) axis, improve ovarian microcirculation, and exert phytoestrogenic effects. Clinical studies, including Phase 4 trials, have evaluated its efficacy in improving ovarian reserve markers such as antral follicle count (AFC) and anti-Müllerian hormone (AMH) levels in women undergoing assisted reproductive technologies like IVF-ET.
- Brand names
- HengyanKuntai Capsules
- Other names
- Kuntai JiaonangKuntai Capsules
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)EGFR (Epidermal growth factor receptor)EGR1 (Early growth response protein 1)TGFβ ligands (TGF-β ligand superfamily)IL-6 (Interleukin 6)JUN (Transcription factor Jun)TP53 (Cellular Tumor Antigen p53 R175H)ER (Estrogen receptor)
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