Hepad S1

Hepad S1 is an herbal medicine used primarily in the context of **Parkinson’s disease (PD)** research. It has been demonstrated, in both in vitro and in vivo rodent PD models, to exert **antioxidant and neuroprotective effects** on dopaminergic neurons of the substantia nigra. Mechanistically, Hepad S1 pretreatment protects against oxidative stress by recovering reduced glutathione levels, decreasing lipid peroxidation, recovering mitochondrial complex I activity, and preserving tyrosine hydroxylase-positive dopaminergic neurons. It also enhances dopamine availability and increases serum serotonin and orexin A in animal models. The precise constituent herbs and molecular mechanisms are not detailed in available literature, but its effects are attributed to the overall antioxidative activity and support of dopaminergic neuronal survival[1].

Brand names

Hepad S1

Other names

Hepad