Drug intelligence / Profile preview

Hepano

Development stage
Preclinical
Lead developer
Dabur India
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Hepano is a polyherbal Ayurvedic formulation developed by Himalaya Wellness Company for the management of liver disorders, specifically non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH). It is composed of five specific herbs: *Tinospora cordifolia*, *Ricinus communis*, *Phyllanthus amarus*, *Boerhavia diffusa*, and *Terminalia chebula*. Preclinical studies have demonstrated that Hepano offers hepatoprotection by modulating hepatic and circulating lipids, including phospholipids and ceramides, and by exhibiting anti-inflammatory and anti-fibrotic properties. It is used to mitigate liver damage, obesity, and insulin resistance induced by high-fat, high-fructose diets.

Brand names
Hepano
Other names
Himalaya Hepano

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