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hepatitis b antigen
- Development stage
- Approved
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Hepatitis B antigen most commonly refers to the hepatitis B surface antigen (HBsAg), a protein present on the outer envelope of the hepatitis B virus (HBV). HBsAg is used as a marker in blood tests to detect acute or chronic HBV infection. Its presence in blood indicates that a person is currently infected with HBV and can transmit the virus to others. The detection of this antigen is one of the earliest signs of infection and forms part of standard diagnostic panels for hepatitis B. In addition to its diagnostic role, purified recombinant HBsAg is also used as the active component in all current hepatitis B vaccines. Mechanistically, it acts as an immunogen—stimulating an immune response that leads to antibody production against HBV[1][5][6].
- Brand names
- Engerix-BRecombivax HBHeplisav-BPreHevbrioSci-B-VacFendrixBiovac-BElovac BGeneVac-BShanvac-B
- Other names
- hepatitis B surface antigenHBsAgAustralia antigen
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