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Hepatitis B-Imperial College London-Hepatitis B-Tetanus
- Development stage
- Unknown
- Lead developer
- Imperial College London
- Modality
- Vaccines & Immunotherapeutics
01
Overview
Hepatitis B-Imperial College London-Hepatitis B-Tetanus refers to a combination of routine vaccinations—specifically the Hepatitis B surface antigen (HBsAg) vaccine and the Tetanus toxoid vaccine (often administered as Td/IPV)—used within a clinical research framework at Imperial College London. The primary study (NCT03531710) utilizing these vaccines is an exploratory investigation into the maturation of human B cells following immunization. By characterizing the memory B cell responses to these well-established vaccines, researchers aim to gain insights that could inform the design of more effective vaccines for complex pathogens, such as HIV. The Hepatitis B component induces immunity against the Hepatitis B virus (HBV) using recombinant surface antigens, while the Tetanus component provides protection against the neurotoxin produced by Clostridium tetani.
- Other names
- Hepatitis B vaccineTetanus vaccineTd/IPVHBsAg vaccineHepatitis B-Imperial College London-Hepatitis B-Tetanus
02
Targets
HBsAg (Hepatitis B surface antigen)TT (Tetanus toxoid)
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