Drug intelligence / Profile preview

Heptex

Development stage
Phase 2
Lead developer
Natural Wellness Biotech
Administration
Oral
01

Overview

Heptex is an oral proprietary herbal medicinal product containing powdered extracts of **Phyllanthus niruri** aerial parts and **Silybum marianum** fruit. Each capsule contains 200 mg of Dukung Anak and 100 mg of milk thistle. It has been developed by Natural Wellness as a hepatoprotective, antioxidant botanical product for people with apparent risk factors for nonalcoholic steatohepatitis. In a randomized phase II trial, Heptex was well tolerated over 36 weeks, but changes in ALT, AST, fibrosis measures, and liver-fat measures were not significantly different from placebo between treatment groups; its clinical efficacy therefore remains unconfirmed.

Brand names
Heptex
Other names
Phyllanthus niruri and Silybum marianum combinationDukung Anak and Milk Thistle combination
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))

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