Drug intelligence / Profile preview

hericium erinaceus extract

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Hericium erinaceus extract, commonly known as Lion's Mane mushroom extract, is a botanical substance derived from the fruiting bodies or mycelia of the *Hericium erinaceus* fungus. It is widely utilized in traditional medicine and as a dietary supplement for its purported nootropic and neuroprotective effects. The extract contains two primary classes of bioactive compounds: hericenones (found in the fruiting body) and erinacines (found in the mycelium), both of which are capable of crossing the blood-brain barrier. These compounds are thought to stimulate the synthesis of Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF), thereby promoting hippocampal neurogenesis and supporting the survival of cholinergic neurons. Clinical investigations have focused on its potential therapeutic utility in treating mild cognitive impairment, Alzheimer's disease, depression, and anxiety disorders.

Brand names
WeibaoMycoThrive
Other names
Lion's Mane mushroom extractYamabushitakeHoutouSatyr's BeardBearded Tooth MushroomHericium erinaceus
02

Targets

BDNF (Brain-derived neurotrophic factor)NGF (Nerve growth factor)

Beyond the preview

Go deeper on hericium erinaceus extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on hericium erinaceus extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call