Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
hESC-derived midbrain dopaminergic neurons
- Development stage
- Unknown
- Lead developer
- S.Biomedics
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Implant
01
Overview
hESC-derived midbrain dopaminergic neurons are an investigational cell therapy for the treatment of Parkinson's disease. This regenerative medicine approach involves the large-scale differentiation of clinical-grade human embryonic stem cells (hESCs) into high-purity midbrain dopaminergic (mDA) progenitor cells under Good Manufacturing Practice (GMP) conditions. The cells are surgically transplanted into the putamen or striatum, where they are intended to mature into functional dopaminergic neurons, integrate into the host brain, and restore dopaminergic innervation. By replacing the neurons lost in the substantia nigra, the therapy aims to provide sustained symptomatic relief and potentially modify the disease course. Key clinical programs include S. Biomedics' TED-A9 and the GForce-PD consortium's STEM-PD.
- Other names
- hESC-mDAshuman embryonic stem cell-derived midbrain dopaminergic neuronsSTEM-PD
Beyond the preview
Go deeper on hESC-derived midbrain dopaminergic neurons.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on hESC-derived midbrain dopaminergic neurons.