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Hewei Jiangni Decoction
- Development stage
- Unknown
- Lead developer
- Beijing University of Chinese Medicine East Hospital
- Administration
- Oral
01
Overview
Hewei Jiangni Decoction is a Traditional Chinese Medicine (TCM) herbal formula primarily investigated for the treatment of non-erosive gastroesophageal reflux disease (NERD). Developed by researchers at the Dongfang Hospital of Beijing University of Chinese Medicine, the decoction is formulated to address the TCM pattern of "stomach qi rebellion" by harmonizing the stomach and directing qi downward. Clinical studies have compared its efficacy to proton pump inhibitors like omeprazole, focusing on its ability to alleviate symptoms such as heartburn, acid regurgitation, and chest pain while potentially offering a lower recurrence rate. The formula typically consists of multiple botanical extracts aimed at improving gastric motility and reducing esophageal mucosal sensitivity.
- Other names
- Hewei Jiangni formulaHewei Jiangni Tang和胃降逆方
02
Targets
TRPV1 (Transient receptor potential cation channel subfamily V member 1)IL-6 (Interleukin 6)MMP9 (Matrix metalloproteinase-9)IL8 (C-X-C Motif Chemokine Ligand 8)EGFR T790M (Epidermal growth factor receptor T790M mutant)STIM1 (Stromal interaction molecule 1)IL1B (Interleukin-1 beta)
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