Drug intelligence / Profile preview

heweitongxie

Development stage
Preclinical
Lead developer
Chengdu University of Traditional Chinese Medicine
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Heweitongxie (also known as He-Wei-Tong-Xie or HWXT) is a traditional Chinese medicine (TCM) herbal formulation derived from the classical Large Chengqi Decoction. It is composed of multiple herbal ingredients including Codonopsis pilosula (C. pilosula), Poria cocos (P. cocos), Atractylodes macrocephala (A. macrocephala), Citrus reticulata (C. reticulata), Pinellia ternate (P. ternate), and others[2]. The formulation has been studied for its therapeutic effects in acute pancreatitis complicated with gastrointestinal dysfunction and has also been investigated for use in functional constipation in elderly patients with "spleen and stomach weakness" according to TCM theory[1][3]. In clinical studies, administration of HWTX was associated with significant improvement in gastrointestinal symptoms such as stomach ache, abdominal distension, borborygmus, and defecation compared to standard care alone[1]. The mechanism of action is not fully elucidated but is presumed to involve modulation of gastrointestinal function through multi-herbal synergistic effects typical of TCM formulations.

Brand names
heweitongxie
Other names
He-Wei-Tong-Xie decoctionHWXT decoctionHWTX granules

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