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hexavalent group b streptococcus conjugate vaccine
- Development stage
- Phase 1
- Lead developer
- Pfizer
- Modality
- Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Hexavalent group B streptococcus conjugate vaccine is a multivalent vaccine candidate being developed by Ningbo Rong'an Biological Pharmaceutical, a subsidiary of AIM Vaccine. It is designed to prevent Group B Streptococcus (GBS) infections, which are a leading cause of neonatal sepsis, pneumonia, and meningitis. The vaccine utilizes a conjugate technology platform, linking capsular polysaccharides from six common GBS serotypes to a carrier protein to enhance immunogenicity and induce a T-cell dependent immune response. The primary development strategy involves maternal immunization to provide passive protection to infants through the transplacental transfer of protective antibodies.
- Other names
- 6-valent GBS conjugate vaccinehexavalent GBS vaccine
02
Targets
GBS CPS (Group B Streptococcus capsular polysaccharide)
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