Drug intelligence / Profile preview

hexoprenaline

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Intravenous, Inhalation
01

Overview

Hexoprenaline is a selective beta-2 adrenergic receptor agonist and small molecule drug used primarily as a bronchodilator, antiasthmatic, and tocolytic agent. It acts by stimulating beta-2 adrenergic receptors in smooth muscle, leading to relaxation of bronchial and uterine muscles. This results in bronchodilation for the treatment of asthma and other obstructive airway diseases (such as bronchitis and emphysema), as well as inhibition of uterine contractions for the management of preterm labor (tocolysis). Hexoprenaline is available in oral, intravenous, and inhalation formulations. It has been marketed under various brand names including Gynipral (notably in Russia and Switzerland) but is not approved by the US FDA[1][3][4][5][6]. Its clinical use is supported by studies showing effective bronchodilation with generally fewer side effects compared to some other agents[4].

Brand names
GynipralIpradol
Other names
hexoprenalineEsoprenalinaHexoprenalino
02

Targets

ADRB2 (β2)

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