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Hexue Tongbi Powder
- Development stage
- Unknown
- Lead developer
- First Affiliated Hospital of Guangzhou University of Chinese Medicine
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Hexue Tongbi Powder is a Traditional Chinese Medicine (TCM) herbal formulation developed by The First Affiliated Hospital of Guangzhou University of Chinese Medicine. It is specifically designed as an external adjuvant therapy for patients with colorectal cancer experiencing oxaliplatin-induced peripheral neuropathy (OIPN). The formulation is typically administered as a topical soak (hand or foot bath). According to TCM principles, the powder functions to harmonize the blood, resolve blood stasis, and unblock the collaterals, addressing the underlying pathogenesis of chemotherapy-induced nerve damage. Clinical research indicates that it may alleviate sensory symptoms such as numbness, tingling, and cold-induced paresthesia by improving local microcirculation and potentially exerting anti-inflammatory effects on peripheral nerve endings.
- Other names
- Hexue Tongbi San和血通痹散
02
Targets
BCL-2 (BCL-2 family)TRPV1 (Transient receptor potential cation channel subfamily V member 1)
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