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Hezhong Jianpi Fang (和中健脾方) is a Traditional Chinese Medicine (TCM) formula. Its name translates to "Harmonizing Middle and Strengthening Spleen Formula," indicating its primary therapeutic actions according to TCM principles. It is traditionally used to address conditions related to spleen and stomach weakness, such as indigestion, abdominal distension, and loose stools. Recent clinical observations suggest that Hezhong Jianpi Fang may improve the expression of gastrointestinal hormones like Vasoactive Intestinal Peptide (VIP) and Motilin (MOT), and modulate inflammatory factors, potentially offering benefits in conditions such as PPI-dependent gastroesophageal reflux disease.
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