Drug intelligence / Profile preview

HFB3-1

Development stage
Unknown
Lead developer
HiFiBiO Therapeutics
01

Overview

HFB3-1: sourced facts only. name: "We investigated the pharmacokinetic (PK), pharmacodynamics (PD), and anti-tumor efficacy of an anti-TNFR2 agonist, HFB3-1, and an anti-OX40 agonist, HFB10-1, in syngeneic tumor models." [DOI:10.1158/1538-7445.am2024-7176]; target: "We investigated the pharmacokinetic (PK), pharmacodynamics (PD), and anti-tumor efficacy of an anti-TNFR2 agonist, HFB3-1, and an anti-OX40 agonist, HFB10-1, in syngeneic tumor models." [DOI:10.1158/1538-7445.am2024-7176]; developer: "1HiFiBiO Therapeutics, Cambridge, MA." [DOI:10.1158/1538-7445.am2024-7176]; stage: "We investigated the pharmacokinetic (PK), pharmacodynamics (PD), and anti-tumor efficacy of an anti-TNFR2 agonist, HFB3-1, and an anti-OX40 agonist, HFB10-1, in syngeneic tumor models." [DOI:10.1158/1538-7445.am2024-7176]

02

Targets

TNFR2 (Tumor necrosis factor receptor superfamily member 1B)

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