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HH-001 is a humanized monoclonal antibody targeting Ubiquitin Specific Peptidase 22 (USP22), currently in preclinical development by QingHe Biotech for the treatment of androgenetic alopecia and alopecia areata. USP22 is a deubiquitinating enzyme that plays a critical role in protein stability and cell signaling pathways. HH-001 is designed to promote hair growth and follicle regeneration by modulating USP22 activity, which is thought to influence the hair follicle cycle. The drug is intended for subcutaneous administration.
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