Drug intelligence / Profile preview

HH160

Development stage
Phase 1
Lead developer
Huahui Health
Modality
Trispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

HH160 is an investigational trispecific antibody being developed by Huahui Health (Beijing Huahui Health Biotech) for the treatment of solid tumors. As a trispecific antibody, HH160 is engineered to simultaneously bind three different antigens or epitopes. This modality is typically designed to enhance anti-tumor activity by bridging tumor cells with immune effector cells (such as T cells or NK cells) while potentially incorporating a third binding site for costimulation or checkpoint inhibition to overcome the immunosuppressive tumor microenvironment. The drug is currently in the early stages of development within Huahui Health's oncology pipeline.

02

Targets

VEGFA (Vascular endothelial growth factor A)PDCD1 (Programmed cell death protein 1 receptor)CTLA-4 (Cytotoxic t-lymphocyte–associated protein 4)

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