Drug intelligence / Profile preview

hibiscus sabdariffa leaf extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Hibiscus sabdariffa leaf extract is a botanical derivative obtained from the leaves of the Roselle plant, which is traditionally utilized in Southeast Asian medicine and cuisine. While the calyces of the plant are more commonly known for their use in managing hypertension, the leaf extract is distinguished by its high concentration of polyphenolic compounds, including flavonoids such as quercetin and kaempferol, as well as various phenolic acids. Research has demonstrated that the extract possesses significant antioxidant and anti-inflammatory properties, and in vitro studies have indicated potential cytotoxic activity against prostate cancer cells. It is primarily investigated for its ability to modulate oxidative stress and inflammatory signaling pathways, often being consumed as a dietary supplement or as part of traditional therapeutic diets.

Other names
roselle leaf extracthibiscus leaf extract

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