Drug intelligence / Profile preview

high-amylose maize resistant starch type 2

Development stage
Unknown
Lead developer
Ingredion
Modality
Small Molecules, Microbiome Therapeutics
Administration
Oral
01

Overview

High-amylose maize resistant starch type 2 is a dietary fiber ingredient derived from conventionally bred varieties of high-amylose corn. It consists primarily of non-digestible (resistant) starch that resists enzymatic digestion in the small intestine and reaches the colon largely intact. Classified as a "type 2" resistant starch (RS2), it is not chemically modified and is naturally present in certain foods. Its primary mechanisms include improving glycemic management by moderating postprandial blood glucose response, supporting digestive health through fermentation by colonic bacteria to produce short-chain fatty acids, and contributing to energy management. The FDA has authorized a qualified health claim stating that consumption of this ingredient may reduce the risk of type 2 diabetes based on limited scientific evidence[1][2][4]. It is used as a functional food ingredient to replace flour or increase fiber content in various products such as breads, cookies, cereals, and pastas without affecting taste or texture[1][2].

Brand names
HI-MAIZE
Other names
high-amylose corn resistant starchRS2RS-2RS 2resistant starch type 2 from high-amylose maize

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