Drug intelligence / Profile preview

high-PA red DAW

Development stage
Preclinical
Lead developer
INRAE - Unité Expérimentale de Pech Rouge
Modality
Small Molecules
Administration
Oral
01

Overview

high-PA red DAW refers to a high-proanthocyanidin red de-alcoholised wine, a natural product studied for its potential health-protective effects. It contains polyphenols, specifically proanthocyanidins, which are believed to contribute to its biological activities. An intervention study in post-menopausal women evaluated its effects on oxidative DNA damage, gene expression, and blood rheology. The study found that consumption of high-PA red DAW led to blood-fluidifying actions, characterized by a significant decrease in blood viscosity. However, it did not show protective activity against oxidative DNA damage or significantly modify gene expression profiles in peripheral lymphocytes. This product is considered a nutraceutical or dietary supplement due to its food-derived nature and investigated health benefits.

Other names
high-proanthocyanidin red de-alcoholised wine

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