Drug intelligence / Profile preview

Hintonia latiflora extract

Development stage
Phase 3
Lead developer
Harras Pharma Curarina
Modality
Small Molecules
Administration
Oral
01

Overview

Hintonia latiflora extract is a dry concentrate derived from the bark of the Hintonia latiflora tree, a plant native to Central America and Mexico. Traditionally known as Maya Bark or Copalchi, it has been used in folk medicine for its purported health benefits. Modern clinical studies have shown that Hintonia latiflora bark extract can help regulate glucose metabolism and stabilize blood sugar levels in individuals with mild to moderate type 2 diabetes mellitus[1][2][4][7]. The primary active compounds are polyphenols—especially neoflavonoids such as coutareagenin—which are believed to contribute to its antidiabetic effects[1][5][8]. Mechanistically, Hintonia latiflora acts as an inhibitor of alpha-glucosidase, an enzyme responsible for breaking down carbohydrates into glucose; this inhibition slows sugar absorption and helps prevent spikes in blood glucose after meals[5]. Clinical trials have demonstrated significant reductions in fasting and postprandial blood glucose as well as HbA1c values over periods up to 12 months without notable side effects or hypoglycemic episodes[2][7]. It is typically formulated with supportive vitamins (B complex, C, E) and trace minerals (zinc, chromium) for enhanced metabolic support[1][6].

Brand names
Sucontral D
Other names
hintonia latifloraMaya BarkChiapas Treecopalchi
02

Targets

Sucrase-Isomaltase

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