Drug intelligence / Profile preview

HKP107

Development stage
Preclinical
Lead developer
Hankook Korus Pharm
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

HKP107 is a biosimilar monoclonal antibody candidate being developed by Hankook Korus Pharm. It is designed to target the Programmed Cell Death Protein 1 (PD-1) receptor, functioning as an immune checkpoint inhibitor. By blocking the interaction between PD-1 and its ligands (PD-L1 and PD-L2), HKP107 aims to restore and enhance anti-tumor T-cell activity. The drug is a biosimilar of nivolumab (Opdivo) and is currently in the preclinical stage, specifically in process development, for the treatment of various cancers.

Other names
nivolumab biosimilar
02

Targets

PDCD1 (Programmed cell death protein 1 receptor)

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