Drug intelligence / Profile preview

HKP108

Development stage
Preclinical
Lead developer
Hankook Korus Pharm
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

HKP108 is a biosimilar candidate of the anti-PD-1 monoclonal antibody pembrolizumab (Keytruda), currently under development by Hankook Korus Pharm. It is designed to bind to the programmed cell death protein 1 (PD-1) receptor on T cells, preventing its interaction with the ligands PD-L1 and PD-L2. By inhibiting this checkpoint pathway, HKP108 aims to restore and enhance the immune system's ability to detect and destroy cancer cells. The program is in the preclinical stage, with ongoing work focused on process development for its use as an immune checkpoint inhibitor in various oncology indications.

Other names
pembrolizumab biosimilar
02

Targets

PDCD1 (Programmed cell death protein 1 receptor)

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