Drug intelligence / Profile preview

HL186

Development stage
Preclinical
Lead developer
HanAll BioPharma
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

HL186 is a novel monoclonal antibody developed as an immune checkpoint inhibitor targeting T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3). It is being investigated primarily for the treatment of cancer, with the goal of inhibiting tumor growth by modulating immune responses. By blocking TIM-3, HL186 aims to enhance anti-tumor immunity, potentially overcoming resistance mechanisms associated with other checkpoint inhibitors. The drug is part of HanAll Biopharma's oncology pipeline and represents a next-generation approach in immuno-oncology designed to address unmet needs in cancer therapy[5][8][1].

02

Targets

HAVCR2 (T cell immunoglobulin and mucin domain-containing protein 3)

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