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HLB1-006 is a preclinical-stage therapeutic candidate developed by Huonslab, a subsidiary of Huons Global. It functions as a long-acting dual agonist targeting both the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon-like peptide-2 receptor (GLP-2R). The drug is intended for the treatment of short bowel syndrome (SBS), aiming to improve intestinal adaptation, enhance nutrient absorption, and reduce the need for parenteral nutrition in affected patients by leveraging the synergistic effects of GLP-1R and GLP-2R activation.
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