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HLBP-013
- Development stage
- Preclinical
- Lead developer
- HLB Pharma
- Modality
- Small Molecules
- Administration
- Intramuscular
01
Overview
HLBP-013 is a long-acting injectable (LAI) formulation of the dopamine agonist ropinirole, developed using HLB Pharma's proprietary SMEB (Smart Micro-Encapsulation Bio-technology) platform. Designed for the treatment of Parkinson's disease, the SMEB technology utilizes biodegradable polymer microspheres to provide sustained release of the active ingredient over several weeks. This delivery method aims to maintain stable plasma levels of ropinirole, thereby minimizing the 'wearing-off' effect and dyskinesia often associated with the fluctuating drug levels of oral Parkinson's medications. The project is currently in the preclinical and formulation research phase, having transitioned from the pipeline of C-Tri following its acquisition by HLB Pharma.
- Other names
- ropinirole sustained-release injectionropinirole microspheres
02
Targets
DRD3 (Dopamine receptor D3)DRD2 (Dopamine D2 Receptor)
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